Search results for " Antidepressive Agents"

showing 5 items of 5 documents

Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidep…

2021

Contains fulltext : 238693.pdf (Publisher’s version ) (Open Access) Objectives: More than 40 drugs are available to treat affective disorders. Individual selection of the optimal drug and dose is required to attain the highest possible efficacy and acceptable tolerability for every patient.Methods: This review, which includes more than 500 articles selected by 30 experts, combines relevant knowledge on studies investigating the pharmacokinetics, pharmacodynamics and pharmacogenetics of 33 antidepressant drugs and of 4 drugs approved for augmentation in cases of insufficient response to antidepressant monotherapy. Such studies typically measure drug concentrations in blood (i.e. therapeutic …

Drugmedicine.medical_specialtyprecision medicinetherapeutic drug monitoringmedia_common.quotation_subjectStress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13]brain imagingNeuroimagingPsykiatri03 medical and health sciences0302 clinical medicinePharmacotherapyNeuroimagingmedicineHumansIntensive care medicineBiological Psychiatrypharmacogeneticsmedia_commonPsychiatrymedicine.diagnostic_testbusiness.industryAntidepressantsPrecision medicineAntidepressive Agents030227 psychiatryPsychiatry and Mental healthTherapeutic drug monitoringPharmacogeneticsAntidepressants; brain imaging; pharmacogenetics; precision medicine; therapeutic drug monitoring; Antidepressive Agents; Drug Monitoring; Humans; Neuroimaging; Pharmacogenetics; PsychiatryAntidepressants; brain imaging; precision medicine; pharmacogenetics; therapeutic drug monitoringDrug MonitoringbusinessPharmacogeneticsWorld Journal of Biological Psychiatry
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Lavandula angustifolia Essential Oil and Linalool Counteract Social Aversion Induced by Social Defeat

2018

Many vegetable extracts, essential oils, and their main constituents are active on the Central Nervous System (CNS). In fact, they have been used as sedatives, hypnotics, or tranquilizers for their activity in treating CNS disorders. In this research, we studied the possible activities of Lavandula angustifolia (LA) essential oil and of its main constituent, linalool, as anti-stress compounds on anxiety and social interaction and their in vitro effects on proteins (pERK and PKA) involved in the transmission of the signal. An acute intraperitoneal injection of linalool (100 mg/kg) and of LA essential oil (200 mg/kg) reduced motor activity without any anxiolytic effect, but significantly incr…

Central Nervous System30030301 basic medicinelinaloolLavandulaVolatilePharmaceutical SciencePharmacologyAnalytical Chemistrylaw.inventionSocial defeatMicechemistry.chemical_compound0302 clinical medicineAnti-Anxiety AgentsLinaloolCentral Nervous System Diseasessocial defeatlawDrug DiscoveryHypnotics and SedativesEssential oil; Lavandula angustifolia; Linalool; Social defeat; Animals; Anti-Anxiety Agents; Antidepressive Agents; Central Nervous System; Central Nervous System Diseases; Humans; Hypnotics and Sedatives; Interpersonal Relations; Lavandula; Mice; Monoterpenes; Oils Volatile; Analytical Chemistry; Chemistry (miscellaneous); Molecular Medicine; 3003; Drug Discovery3003 Pharmaceutical Science; Physical and Theoretical Chemistry; Organic ChemistryLavandula angustifolia<i>Lavandula angustifolia</i>Antidepressive AgentsLavandulaChemistry (miscellaneous)Molecular MedicineAntidepressantmedicine.drug_classAnxiolyticArticleessential oillcsh:QD241-44103 medical and health scienceslcsh:Organic chemistrymedicineAnimalsHumansInterpersonal RelationsPhysical and Theoretical ChemistryEssential oilbusiness.industryDrug Discovery3003 Pharmaceutical ScienceOrganic Chemistry030104 developmental biologyAnti-Anxiety AgentschemistryLavandula angustifoliaMonoterpenesbusinessOils030217 neurology & neurosurgeryMolecules
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Current Pharmacological Treatment of Painful Diabetic Neuropathy: A Narrative Review.

2020

Background and Objectives: Distal symmetrical polyneuropathy (DSPN) is one of the most common chronic complications of diabetes mellitus. Although it is usually characterized by progressive sensory loss, some patients may develop chronic pain. Assessment of DSPN is not difficult, but the biggest challenge is making the correct diagnosis and choosing the right treatment. The treatment of DSPN has three primary objectives: glycemic control, pathogenic mechanisms, and pain management. The aim of this brief narrative review is to summarize the current pharmacological treatment of painful DSPN. It also summarizes knowledge on pathogenesis-oriented therapy, which is generally overlooked in many p…

medicine.medical_specialtyDiabetic neuropathyAdministration TopicalMEDLINEPregabalinReviewCochrane LibraryDiabetic Neuropathiespharmacological treatmentDiabetes mellitusMedicineHumansPain ManagementpainIntensive care medicinelcsh:R5-920business.industryDiabetes mellitus Neuropathy Pain Pharmacological treatment Administration Topical Analgesics Opioid Anticonvulsants Antidepressive Agents Diabetic Neuropathies Humans Pain ManagementChronic painGeneral Medicinemedicine.diseaseAntidepressive AgentsAnalgesics OpioidNeuropathic paindiabetes mellitusAnticonvulsantsneuropathylcsh:Medicine (General)businessPolyneuropathymedicine.drugMedicina (Kaunas, Lithuania)
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Prevalence of use and appropriateness of antidepressants prescription in acutely hospitalized elderly patients.

2019

Depression is often under-recognized in older patients, even if antidepressants (AD) are commonly prescribed, with a prevalence of use that increase with ageing [ 1 ]. Nevertheless, even if a diagnosis of depression is established, inappropriate treatment can occur [ 2 ]. Beers criteria are the most widely screening tools used to detect inappropriate prescription of drugs in people aged 65 years or more [ 3 ]. Since 2010, attempts to adapt the Beers' criteria have been made in Europe [ 4 , 5 ]. Tricyclic drugs are the ADs to be always avoided in the elderly, owing to their anticholinergic side effects, such as cognitive impairment, delirium, urinary retention and falls [ 3 ]. Selective sero…

Malemedicine.medical_specialtySocio-culturaleInappropriate Prescribing-Potentially inappropriate medication olderPractice Patternsdepression hospitalized patients drugselderlydrugsantidepressivi anzianoPolypharmacy | Inappropriate Prescribing | Medications PIMsantidepressant agent escitalopram paroxetineInternal MedicinemedicineHospital dischargeolderEscitalopramHumansLS4_4Medical prescriptionPractice Patterns Physicians'Depression (differential diagnoses)AgedPolypharmacySertralinePhysicians'antidepressantbusiness.industryTrazodonehospitalized patientsAntidepressive AgentsHospitalizationAcute Disease; Aged; Antidepressive Agents; Female; Humans; Inappropriate Prescribing; Italy; Male; Practice Patterns Physicians'; Hospitalizationantidepressants; elderlyItalyantidepressantsEmergency medicinedepressionAcute DiseasePolypharmacy Inappropriate Prescribing Medications PIMDeliriumFemalePotentially inappropriate medicationmedicine.symptombusinessmedicine.drugEuropean journal of internal medicine
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Italian Association of Sleep Medicine (AIMS) position statement and guideline on the treatment of menopausal sleep disorders

2019

Insomnia, vasomotor symptoms (VMS) and depression often co-occur after the menopause, with consequent health problems and reductions in quality of life. The aim of this position statement is to provide evidence-based advice on the management of postmenopausal sleep disorders derived from a systematic review of the literature. The latter yielded results on VMS, insomnia, circadian rhythm disorders, obstructive sleep apnea (OSA) and restless leg syndrome (RLS). Overall, the studies show that menopausal hormone therapy (MHT) improves VMS, insomnia, and mood. Several antidepressants can improve insomnia, either on their own or in association with MHT; these include selective serotonin reuptake …

Sleep Initiation and Maintenance Disordermedicine.medical_treatmentSerotonin and Noradrenaline Reuptake InhibitorPosition statementSleep medicine0302 clinical medicineSleep Initiation and Maintenance DisordersCognitive behavioraltherapy for insomnia (CBT-I)InsomniaSleep Wake Disorder030212 general & internal medicineContinuous positive airway pressureRestless legs syndromeSerotonin and Noradrenaline Reuptake InhibitorsCognitive behavioraltherapy for insomnia (CBT-I); Hormonereplacementtherapy (HRT); Menopause; Position statement; Sleepdisorders; Vasomotorsymptoms (VMS)Sleep Apnea Obstructive030219 obstetrics & reproductive medicineContinuous Positive Airway PressureDepressionObstetrics and GynecologySerotonin Uptake InhibitorAntidepressive AgentsMenopauseCognitive behavioral therapyCognitive behavioral therapy for insomnia (CBT-I)SleepdisordersAntidepressive AgentFemalemedicine.symptomMenopauseSelective Serotonin Reuptake Inhibitorsmedicine.drugHumanSleep Wake Disordersmedicine.medical_specialtyHormone Replacement TherapyVasomotor symptoms (VMS)MirtazapineCognitive behavioral therapy for insomnia (CBT-I); Hormone replacement therapy (HRT); Menopause; Position statement; Sleep disorders; Vasomotor symptoms (VMS); Antidepressive Agents; Cognitive Behavioral Therapy; Continuous Positive Airway Pressure; Depression; Exercise; Female; Humans; Mirtazapine; Quality of Life; Restless Legs Syndrome; Serotonin Uptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Sleep; Sleep Apnea Obstructive; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Hormone Replacement Therapy; MenopauseMirtazapineSettore MED/10 - Malattie Dell'Apparato RespiratorioHormone replacement therapy (HRT)Hormonereplacementtherapy (HRT)General Biochemistry Genetics and Molecular Biology03 medical and health sciencesRestless Legs Syndromemental disordersmedicineHumansExerciseSleep disorderCognitive Behavioral Therapybusiness.industryVasomotorsymptoms (VMS)medicine.diseasenervous system diseasesObstructive sleep apneaMenopause sleep disorders vasomotor symptoms (VMS) hormone replacement therapy (HRT) Cognitive Behavioral Therapy for Insomnia (CBT-I) Position StatementPhysical therapyQuality of LifebusinessSleep
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